Identification and quantification of arterial calcifications in cardiac CT

The amount of coronary artery calcification as quantified with CT images is a strong and independent predictor of cardiovascular events.

The goal of this project is to develop a system for automatic identification, characterization and quantification of calcified plaque in coronary arteries using cardiac CT scans to enable determination of cardiovascular risk in individual patients.

 


Researchers


Papers in international journals

1.J.M. Wolterink, T. Leiner, B.D. de Vos, J-L. Coatrieux, B.M. Kelm, S. Kondo, R.A. Salgado, R. Shahzad, H. Shu, M. Snoeren, R.A.P. Takx, L.J. van Vliet, T. van Walsum, T.P. Willems, G. Yang, Y. Zheng, M.A. Viergever, I. Isgum. An evaluation of automatic coronary artery calcium scoring methods with cardiac CT using the orCaScore framework. Medical Physics, 2016, vol. 43, nr. 5, pp. 2361 ( Abstract | pdf BibTeX)
2.J.M. Wolterink, T. Leiner, R.A.P. Takx, M.A. Viergever, I. Isgum. Automatic coronary calcium scoring in non-contrast-enhanced ECG-triggered cardiac CT with ambiguity detection. IEEE Transactions on Medical Imaging , 2015, vol. 34, nr. 9, pp. 1867-1878 ( Abstract | pdf BibTeX)

Papers in conference proceedings

1. J.M. Wolterink, T. Leiner, R.A.P. Takx, M.A. Viergever, I. Isgum. An automatic machine learning system for coronary calcium scoring in clinical non-contrast enhanced, ECG-triggered cardiac CT. In: SPIE Medical Imaging, 2014, vol. 9035 ( Abstract | pdf BibTeX)

Abstracts

1.J.M. Wolterink, M.J. Willemink, R.A.P. Takx, M. Prokop, J. de Mey, M. Das, P.A. de Jong, R.P.J. Budde, A.M.R. Schilham, R.L.A.W. Bleys, N. Buls, J.E. Wildberger, M.A. Viergever, I. Isgum, T. Leiner. Differences in coronary artery calcification scores obtained with different CT scanners are not software related. Society of Cardiovascular Computed Tomography, 9th Annual Scientific Meeting, 2014 ( Abstract | pdf BibTeX)
2.J.M. Wolterink, T. Leiner, P.A. de Jong, M.A. Viergever, I. Isgum. Automatic coronary calcium scoring in ECG-triggered cardiac CT. Radiological Society of North America, 99th Annual Meeting, 2013 ( Abstract | pdf BibTeX)